"Mice treated with THC alone showed no improvement in glucose regulation, a key indicator of type 2 diabetes. Despite losing weight, these animals continued to exhibit impaired glucose homeostasis, a hallmark of diabetes.
In contrast, mice treated with the whole cannabis extract not only lost weight but also experienced a reversal of these metabolic impairments."
Cannabis is so much more than just THC and CBD. There’s hundreds of different compounds- terpenes and flavonoids alone completely change how one strain or sample affects an individual. It’s honestly a travesty that it’s been demonized and locked away from real research.
For decades I’ve managed so many aspects of my health through very intentional dosing. I know the dominant terpene profiles I have the most success with along with the different THC:CBD ratios. Unfortunately, I had to give up something that worked perfectly for me as I have no income and insurance obviously won’t cover cannabis. It’s so demoralizing being back on prescribed drugs that not only don’t feel good or work as well with my mind and body, but can literally kill me if I take too much or stop incorrectly.
Beyond THC sounds like a synthetic cannabis startup
Given weed’s increasing legality it would be interesting to follow a human cohort and see if this holds true for people, too. I’ve kept 50+ pounds off for like 10 years? now and have been a daily user that entire time, it’s interesting to think that may have helped. Especially since I know studies say long term weight loss is uncommon.
THCV compounds have been noted for their appetite suppressing effects, and strains that have high THCV tend to not give people munchies or cause them to melt into the couch.
Do you happen to have a citation for this? I’m interested because those are the exact opposite effects I need, (I need appetite stimulation and couchlock/relaxation for sleep), and the dispensaries I’m heading to in a couple weeks maaaaay be able to help with that.
https://www.leafly.com/news/cannabis-101/what-is-thcv-and-what-are-the-benefits-of-this-cannabinoid
It is a little bit difficult to identify the strains that have high THCV content. Tansie and “diesels” tend to be the number one cultivars for high THCV, but I have also seen concentrates in prepackaged vape pods that market their THCV content.
I do not smoke weed very often, even though I’m in a legal state, maybe three or four times a year, but when I do, I tend to go for those because it also helps decrease anxiety.
I wish it was legal here in the UK. I have been a fat bastard all my life except for the 5 or so years I was on the weed. I was working at mcdonalds too grazing so much stock on shift.
In mice.
Nature made weed. Man made percocet. Who do you trust?
“Nature” also made opium/morphine, arsenic and ricin.
I’m a big fan of cannabis, but you cannot fall into the “natural means safe” trap.
https://en.wikipedia.org/wiki/Appeal_to_nature
Appeal to Nature fallacy. MAHA runs on this and a lot of thinking that leads to the alt-right, so good on calling this out.
I used to live in a very “crunchy” area with hippies and would catch weird speaking points occasionally, it picked up over the last few years and now they’re all MAHA or adjacent.
Its a play on an old joke. God made weed, man made beer. Who do you trust?
Its a play on an old joke. God made weed, man made beer. Who do you trust?
Fair enough, but the “it’s natural, so it has to be good,” or “it’s not natural, so it’s bad” is constantly being used
simlar to omezpic, and they are increasingly trying to restrict it.
So stuff and things beyond weed may help, but weed does help.
